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A randomised controlled trial published in Diabetes Care reported that co-administration of probiotics with GLP-1 therapy resulted in significant improvements in fasting glucose levels and cholesterol profiles, suggesting an additive effect on metabolic parameters

Novo Nordisk clearly has a building efficacy in its commercial and under review (FDA: Wegovy HD and CagriSema) assets

Wegovy is approved specifically for chronic weight management at the higher 2.4 mg maintenance dose

If constipation is particularly troublesome, discuss with your prescriber whether adjusting your GLP-1 medication dose or slowing the titration schedule might help manage symptoms while maintaining therapeutic benefits

Beyond 3 months: The rate of regain slows but does not always stop

Stay Accountable with Regular Check-Ins Accountability plays a huge role in weight loss